Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme.

Cdk-interacting protein 1 (Cip1) is a p53-regulated 21-kDa protein that inhibits several members of the cyclin-dependent kinase (CDK) family. It was initially observed in complexes containing CDK4, cyclin D, and proliferating cell nuclear antigen (PCNA). PCNA, in conjunction with activator 1, acts a...

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發表在:	Proc Natl Acad Sci U S A
Principais autores:	Flores-Rozas, H, Kelman, Z, Dean, F B, Pan, Z Q, Harper, J W, Elledge, S J, O'Donnell, M, Hurwitz, J
格式:	Artigo
語言:	Inglês
出版:	National Academy of Sciences 1994
主題:	Research Article
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44665/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7915843/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.18.8655
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