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Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme.

Cdk-interacting protein 1 (Cip1) is a p53-regulated 21-kDa protein that inhibits several members of the cyclin-dependent kinase (CDK) family. It was initially observed in complexes containing CDK4, cyclin D, and proliferating cell nuclear antigen (PCNA). PCNA, in conjunction with activator 1, acts a...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Flores-Rozas, H, Kelman, Z, Dean, F B, Pan, Z Q, Harper, J W, Elledge, S J, O'Donnell, M, Hurwitz, J
פורמט: Artigo
שפה:Inglês
יצא לאור: 1994
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC44665/
https://ncbi.nlm.nih.gov/pubmed/7915843
תגים: הוספת תג
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