NQO1 Stabilizes p53 in Response to Oncogene-Induced Senescence

Cellular senescence is a state of permanent cellular arrest that provides an initial barrier to cell transformation and tumorigenesis. In this study, we report that expression of NAD(P)H:quinone oxidoreductase 1 (NQO1), a cytoplasmic 2-electron reductase, is induced during oncogene-induced senescenc...

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Bibliografiske detaljer
Udgivet i:Int J Biol Sci
Main Authors: Liu, Kaiyu, Jin, Bo, Wu, Chenglin, Yang, Jianming, Zhan, Xiangwen, Wang, Le, Shen, Xiaomeng, Chen, Jing, Chen, Hao, Mao, Zebin
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466457/
https://ncbi.nlm.nih.gov/pubmed/26078718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.11978
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