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Characterization of the p53 Response to Oncogene-Induced Senescence

BACKGROUND: P53 activation can trigger various outcomes, among them reversible growth arrest or cellular senescence. It is a live debate whether these outcomes are influenced by quantitative or qualitative mechanisms. Furthermore, the relative contribution of p53 to Ras-induced senescence is also ma...

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Detalhes bibliográficos
Main Authors: Ruiz, Lidia, Traskine, Magali, Ferrer, Irene, Castro, Estrella, Leal, Juan F. M., Kaufman, Marcelline, Carnero, Amancio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2535567/
https://ncbi.nlm.nih.gov/pubmed/18800172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003230
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