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Hey bHLH Proteins Interact with a FBXO45 Containing SCF Ubiquitin Ligase Complex and Induce Its Translocation into the Nucleus

The Hey protein family, comprising Hey1, Hey2 and HeyL in mammals, conveys Notch signals in many cell types. The helix-loop-helix (HLH) domain as well as the Orange domain, mediate homo- and heterodimerization of these transcription factors. Although distinct interaction partners have been identifie...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Salat, Daniela, Winkler, Anja, Urlaub, Henning, Gessler, Manfred
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466309/
https://ncbi.nlm.nih.gov/pubmed/26068074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130288
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