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Standardization of the experimental autoimmune myasthenia gravis (EAMG) model by immunization of rats with Torpedo californica acetylcholine receptors — Recommendations for methods and experimental designs

Myasthenia gravis (MG) with antibodies against the acetylcholine receptor (AChR) is characterized by a chronic, fatigable weakness of voluntary muscles. The production of autoantibodies involves the dysregulation of T cells which provide the environment for the development of autoreactive B cells. T...

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Détails bibliographiques
Publié dans:Exp Neurol
Auteurs principaux: Losen, Mario, Martinez-Martinez, Pilar, Molenaar, Peter C., Lazaridis, Konstantinos, Tzartos, Socrates, Brenner, Talma, Duan, Rui-Sheng, Luo, Jie, Lindstrom, Jon, Kusner, Linda
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466156/
https://ncbi.nlm.nih.gov/pubmed/25796590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2015.03.010
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