Guidelines for pre-clinical assessment of the acetylcholine receptor-specific passive transfer myasthenia gravis model - recommendations for methods and experimental designs

Antibodies against the muscle acetylcholine receptor (AChR) are the most common cause of myasthenia gravis (MG). Passive transfer of AChR antibodies from MG patients into animals reproduces key features of human disease, including antigenic modulation of the AChR, complement-mediated damage of the n...

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Detalhes bibliográficos
Publicado no:Exp Neurol
Main Authors: Kusner, Linda L., Losen, Mario, Vincent, Angela, Lindstrom, Jon, Tzartos, Socrates, Lazaridis, Konstantinos, Martinez-Martinez, Pilar
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466131/
https://ncbi.nlm.nih.gov/pubmed/25743217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2015.02.025
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