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X-ray structures of isoforms of the actin-binding protein profilin that differ in their affinity for phosphatidylinositol phosphates.

We determined the structures of Acanthamoeba profilin I and profilin II by x-ray crystallography at resolutions of 2.0 and 2.8 A, respectively. The polypeptide folds and the actin-binding surfaces of the amoeba profilins are very similar to those of bovine and human profilins. The electrostatic pote...

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Detalhes bibliográficos
Main Authors: Fedorov, A A, Magnus, K A, Graupe, M H, Lattman, E E, Pollard, T D, Almo, S C
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC44661/
https://ncbi.nlm.nih.gov/pubmed/8078936
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