Essential Role of Interleukin-12/23p40 in the Development of Graft-versus-Host Disease in Mice

Graft-versus-host disease (GVHD), in both its acute (aGVHD) and chronic (cGVHD) forms, remains a major obstacle impeding successful allogeneic hematopoietic stem cell transplantation (allo-HSCT). T cells, in particular pathogenic Th1 and Th17 subsets, are a driving force for the induction of GVHD. I...

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Vydáno v:Biol Blood Marrow Transplant
Hlavní autoři: Wu, Yongxia, Bastian, David, Schutt, Steven, Nguyen, Hung, Fu, Jianing, Heinrichs, Jessica, Xia, Changqing, Yu, Xue-Zhong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466028/
https://ncbi.nlm.nih.gov/pubmed/25846718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2015.03.016
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