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In Situ Peptide-MHC-II Tetramer Staining of Antigen-Specific CD4(+) T Cells in Tissues

The invention of peptide-MHC-tetramer technology to label antigen-specific T cells has led to an enhanced understanding of T lymphocyte biology. Here we describe the development of an in situ pMHC-II tetramer staining method to visualize antigen-specific CD4(+) T cells in tissues. This method comple...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Dileepan, Thamotharampillai, Kim, Hyeon O., Cleary, P. Patrick, Skinner, Pamela J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465905/
https://ncbi.nlm.nih.gov/pubmed/26067103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128862
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