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Impact of Inhibiting Ileal Apical Versus Basolateral Bile acid Transport on Cholesterol Metabolism and Atherosclerosis in Mice

BACKGROUND: Bile acid sequestrants have been used for many years to treat hypercholesterolemia by increasing hepatic conversion of cholesterol to bile acids, thereby inducing hepatic LDL receptor expression and clearance of apoB-containing particles. In order to further understand the underlying mol...

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Vydáno v:Dig Dis
Hlavní autor: Dawson, Paul A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465549/
https://ncbi.nlm.nih.gov/pubmed/26045273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000371691
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