Carriers of a common variant in the dopamine transporter gene have greater dementia risk, cognitive decline, and faster ventricular expansion

BACKGROUND: Genetic variants in DAT1, the gene encoding the dopamine transporter protein (DAT), have been implicated in many brain disorders. In a recent case-control study of Alzheimer’s disease (AD), a regulatory polymorphism in DAT1 showed a significant association with the clinical stages of dem...

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Enregistré dans:
Détails bibliographiques
Publié dans:Alzheimers Dement
Auteurs principaux: Roussotte, Florence F., Gutman, Boris A., Hibar, Derrek P., Madsen, Sarah K., Narr, Katherine L., Thompson, Paul M.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465053/
https://ncbi.nlm.nih.gov/pubmed/25496873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2014.10.011
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