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A Direct Interaction With RNA Dramatically Enhances the Catalytic Activity of the HIV-1 Protease In Vitro
Though the steps of human immunodeficiency virus (HIV)-1 virion maturation are well documented, the mechanisms regulating the proteolysis of the Gag and Gag-Pro-Pol polyproteins by the HIV-1 protease (PR) remain obscure. One proposed mechanism argues that the maturation intermediate p15NC must inter...
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| Publicado no: | J Mol Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4465046/ https://ncbi.nlm.nih.gov/pubmed/25986307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.05.007 |
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