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OXIDATIVE STRESS AND TREG DEPLETION IN LUPUS PATIENTS WITH ANTI-PHOSPHOLIPID SYNDROME

Anti-phospholipid antibodies (APLA) represent a diagnostic criterion of systemic lupus erythematosus (SLE) and cause morbidity, termed anti-phospholipid syndrome (APS). Activation of the mechanistic target of rapamycin (mTOR) has been recently associated with APS. mTOR is a sensor of oxidative stres...

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Detalhes bibliográficos
Publicado no:Clin Immunol
Main Authors: Lai, Zhi-wei, Marchena-Mendez, Ivan, Perl, Andras
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464983/
https://ncbi.nlm.nih.gov/pubmed/25862984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2015.03.024
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