A Multi-center Phase I Dose Escalation Trial to Evaluate Safety and Tolerability of Intra-arterial Temozolomide for Patients with Advanced Extremity Melanoma Using Normothermic Isolated Limb Infusion

This phase I trial reports the first use of intra arterial temozolomide via isolated limb infusion for patients with advanced extremity melanoma. There was minimal toxicity and the maximum tolerated dose was determined.

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Vydáno v:Ann Surg Oncol
Hlavní autoři: Beasley, Georgia M., Speicher, Paul, Augustine, Christina K., Dolber, Paul C., Peterson, Bercedis L., Sharma, Ketan, Mosca, Paul J., Royal, Richard, Ross, Merrick, Zager, Jonathan S., Tyler, Douglas S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464816/
https://ncbi.nlm.nih.gov/pubmed/25145500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-014-3887-z
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