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Activation of Cannabinoid CB(2) receptors Reduces Hyperalgesia in an Experimental Autoimmune Encephalomyelitis Mouse Model of Multiple Sclerosis
Clinical trials investigating the analgesic efficacy of cannabinoids in multiple sclerosis have yielded mixed results, possibly due to psychotropic side effects mediated by cannabinoid CB(1) receptors. We hypothesized that a CB(2)-specific agonist (JWH-133) would decrease hyperalgesia in an experime...
Kaydedildi:
Yayımlandı: | Neurosci Lett |
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Asıl Yazarlar: | , |
Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
2015
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4464808/ https://ncbi.nlm.nih.gov/pubmed/25849525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2015.04.002 |
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