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Activation of Cannabinoid CB(2) receptors Reduces Hyperalgesia in an Experimental Autoimmune Encephalomyelitis Mouse Model of Multiple Sclerosis
Clinical trials investigating the analgesic efficacy of cannabinoids in multiple sclerosis have yielded mixed results, possibly due to psychotropic side effects mediated by cannabinoid CB(1) receptors. We hypothesized that a CB(2)-specific agonist (JWH-133) would decrease hyperalgesia in an experime...
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| Publicado no: | Neurosci Lett |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4464808/ https://ncbi.nlm.nih.gov/pubmed/25849525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2015.04.002 |
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