6-7-Dimethoxy-4-methylcoumarin suppresses pro-inflammatory mediator expression through inactivation of the NF-κB and MAPK pathways in LPS-induced RAW 264.7 cells

In this study, we investigated the ability of 6,7-dimethoxy-4-methylcoumarin (DMC) to inhibit lipopolysaccharide (LPS)-induced expression of pro-inflammatory mediators in mouse macrophage (RAW 264.7) cells, and the molecular mechanism through which this inhibition occurred. Our results indicated tha...

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Veröffentlicht in:EXCLI J
Hauptverfasser: Kim, Kil-Nam, Yang, Hye-Won, Ko, Seok-Chun, Ko, Yeong-Jong, Kim, Eun-A, Roh, Seong Woon, Ko, Eun-Yi, Ahn, Ginnae, Heo, Soo-Jin, Jeon, You-Jin, Yoon, Weon-Jong, Hyun, Chang-Gu, Kim, Daekyung
Format: Artigo
Sprache:Inglês
Veröffentlicht: Leibniz Research Centre for Working Environment and Human Factors 2014
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464263/
https://ncbi.nlm.nih.gov/pubmed/26417302
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