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Combinatorial optimization of synthetic operons for the microbial production of p-coumaryl alcohol with Escherichia coli

BACKGROUND: Microbes are extensively engineered to produce compounds of biotechnological or pharmaceutical interest. However, functional integration of synthetic pathways into the respective host cell metabolism and optimization of heterologous gene expression for achieving high product titers is st...

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Détails bibliographiques
Publié dans:Microb Cell Fact
Auteurs principaux: van Summeren-Wesenhagen, Philana V, Voges, Raphael, Dennig, Alexander, Sokolowsky, Sascha, Noack, Stephan, Schwaneberg, Ulrich, Marienhagen, Jan
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464236/
https://ncbi.nlm.nih.gov/pubmed/26062542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-015-0274-9
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