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Osteopontin mediates survival, proliferation and migration of neural stem cells through the chemokine receptor CXCR4

INTRODUCTION: Osteopontin (OPN) is a phosphoglycoprotein with important roles in tissue homeostasis, wound healing, immune regulation, and stress responses. It is expressed constitutively in the brain and upregulated during neuroinflammatory responses; for example, after focal cerebral ischemia. To...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Rabenstein, Monika, Hucklenbroich, Joerg, Willuweit, Antje, Ladwig, Anne, Fink, Gereon Rudolf, Schroeter, Michael, Langen, Karl-Josef, Rueger, Maria Adele
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464234/
https://ncbi.nlm.nih.gov/pubmed/25998490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-015-0098-x
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