Abnormal Mitochondrial Function and Impaired Granulosa Cell Differentiation in Androgen Receptor Knockout Mice

In the ovary, the paracrine interactions between the oocyte and surrounded granulosa cells are critical for optimal oocyte quality and embryonic development. Mice lacking the androgen receptor (AR(−/−)) were noted to have reduced fertility with abnormal ovarian function that might involve the promot...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Wang, Ruey-Sheng, Chang, Heng-Yu, Kao, Shu-Huei, Kao, Cheng-Heng, Wu, Yi-Chen, Yeh, Shuyuan, Tzeng, Chii-Reuy, Chang, Chawnshang
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463620/
https://ncbi.nlm.nih.gov/pubmed/25941928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16059831
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