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Enhanced Conformational Sampling Using Replica Exchange with Concurrent Solute Scaling and Hamiltonian Biasing Realized in One Dimension

[Image: see text] Replica exchange (REX) is a powerful computational tool for overcoming the quasi-ergodic sampling problem of complex molecular systems. Recently, several multidimensional extensions of this method have been developed to realize exchanges in both temperature and biasing potential sp...

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Bibliografiske detaljer
Udgivet i:J Chem Theory Comput
Main Authors: Yang, Mingjun, Huang, Jing, MacKerell, Alexander D.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2015
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463548/
https://ncbi.nlm.nih.gov/pubmed/26082676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.5b00243
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