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IRX1 hypomethylation promotes osteosarcoma metastasis via induction of CXCL14/NF-κB signaling
Osteosarcoma is a common malignant bone tumor with a propensity to metastasize to the lungs. Epigenetic abnormalities have been demonstrated to underlie osteosarcoma development; however, the epigenetic mechanisms that are involved in metastasis are not yet clear. Here, we analyzed 2 syngeneic prima...
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| Izdano u: | J Clin Invest |
|---|---|
| Glavni autori: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Clinical Investigation
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4463198/ https://ncbi.nlm.nih.gov/pubmed/25822025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI78437 |
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