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An epigenetically distinct breast cancer cell subpopulation promotes collective invasion

Tumor cells can engage in a process called collective invasion, in which cohesive groups of cells invade through interstitial tissue. Here, we identified an epigenetically distinct subpopulation of breast tumor cells that have an enhanced capacity to collectively invade. Analysis of spheroid invasio...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Westcott, Jill M., Prechtl, Amanda M., Maine, Erin A., Dang, Tuyen T., Esparza, Matthew A., Sun, Han, Zhou, Yunyun, Xie, Yang, Pearson, Gray W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463195/
https://ncbi.nlm.nih.gov/pubmed/25844900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI77767
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