Primary cilium suppression by SREBP1c involves distortion of vesicular trafficking by PLA2G3

Distortion of primary cilium formation is increasingly recognized as a key event in many human pathologies. One of the underlying mechanisms involves aberrant activation of the lipogenic transcription factor sterol regulatory element–binding protein 1c (SREBP1c), as observed in cancer cells. To gain...

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Pubblicato in:Mol Biol Cell
Autori principali: Gijs, Hannah Laura, Willemarck, Nicolas, Vanderhoydonc, Frank, Khan, Niamat Ali, Dehairs, Jonas, Derua, Rita, Waelkens, Etienne, Taketomi, Yoshitaka, Murakami, Makoto, Agostinis, Patrizia, Annaert, Wim, Swinnen, Johannes V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2015
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4462948/
https://ncbi.nlm.nih.gov/pubmed/25904332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-10-1472
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