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Epigenetic modifications of splicing factor genes in myelodysplastic syndromes and acute myeloid leukemia

Somatic mutations in splicing factor genes have frequently been reported in myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). Although aberrant epigenetic changes are frequently implicated in blood cancers, their direct role in suppressing one or both alleles of critical splicing fac...

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Detalles Bibliográficos
Publicado en:Cancer Sci
Main Authors: Wong, Justin J-L, Lau, Katherine A, Pinello, Natalia, Rasko, John E J
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4462368/
https://ncbi.nlm.nih.gov/pubmed/25220401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12532
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