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Epigenetic modifications of splicing factor genes in myelodysplastic syndromes and acute myeloid leukemia

Somatic mutations in splicing factor genes have frequently been reported in myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). Although aberrant epigenetic changes are frequently implicated in blood cancers, their direct role in suppressing one or both alleles of critical splicing fac...

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Dettagli Bibliografici
Pubblicato in:Cancer Sci
Autori principali: Wong, Justin J-L, Lau, Katherine A, Pinello, Natalia, Rasko, John E J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4462368/
https://ncbi.nlm.nih.gov/pubmed/25220401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12532
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