Epigenetic modifications of splicing factor genes in myelodysplastic syndromes and acute myeloid leukemia

Somatic mutations in splicing factor genes have frequently been reported in myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). Although aberrant epigenetic changes are frequently implicated in blood cancers, their direct role in suppressing one or both alleles of critical splicing fac...

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Bibliografiske detaljer
Udgivet i:Cancer Sci
Main Authors: Wong, Justin J-L, Lau, Katherine A, Pinello, Natalia, Rasko, John E J
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2014
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4462368/
https://ncbi.nlm.nih.gov/pubmed/25220401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12532
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