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De-repressing LncRNA-Targeted Genes to Upregulate Gene Expression: Focus on Small Molecule Therapeutics

Non-protein coding RNAs (ncRNAs) make up the overwhelming majority of transcripts in the genome and have recently gained attention for their complex regulatory role in cells, including the regulation of protein-coding genes. Furthermore, ncRNAs play an important role in normal development and their...

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Vydáno v:Mol Ther Nucleic Acids
Hlavní autoři: Fatemi, Roya Pedram, Velmeshev, Dmitry, Faghihi, Mohammad Ali
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461991/
https://ncbi.nlm.nih.gov/pubmed/25405465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2014.45
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