Study on the Dynamic Biological Characteristics of Sca-1(+) Hematopoietic Stem and Progenitor Cell Senescence

The researches in the dynamic changes of the progress of HSCs aging are very limited and necessary. In this study, male C57BL/6 mice were divided into 5 groups by age. We found that the superoxide damage of HSPCs started to increase from the middle age (6 months old), with notably reduced antioxidat...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Geng, Shan, Mu, Xin-Yi, Chen, Xiong-Bin, Hou, Ji-Ying, Jia, Dao-Yong, Xu, Chun-Yan, Wang, Ya-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461789/
https://ncbi.nlm.nih.gov/pubmed/26106432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/954120
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