Macrophages expressing arginase 1 and nitric oxide synthase 2 accumulate in the small intestine during Giardia lamblia infection

Nitric oxide (NO) has been shown to inhibit Giardia lamblia in vitro and in vivo. This study sought to determine if Giardia infection induces arginase 1 (ARG1) expression in host macrophages to reduce NO production. Stimulations of RAW 264.7 macrophage-like cells with Giardia extract induced arginas...

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Bibliographic Details
Published in:Microbes Infect
Main Authors: Maloney, Jenny, Keselman, Aleksander, Li, Erqiu, Singer, Steven M.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461514/
https://ncbi.nlm.nih.gov/pubmed/25797399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2015.03.006
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