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Macrophages expressing arginase 1 and nitric oxide synthase 2 accumulate in the small intestine during Giardia lamblia infection

Nitric oxide (NO) has been shown to inhibit Giardia lamblia in vitro and in vivo. This study sought to determine if Giardia infection induces arginase 1 (ARG1) expression in host macrophages to reduce NO production. Stimulations of RAW 264.7 macrophage-like cells with Giardia extract induced arginas...

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Détails bibliographiques
Publié dans:Microbes Infect
Auteurs principaux: Maloney, Jenny, Keselman, Aleksander, Li, Erqiu, Singer, Steven M.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461514/
https://ncbi.nlm.nih.gov/pubmed/25797399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2015.03.006
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