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Macrophages expressing arginase 1 and nitric oxide synthase 2 accumulate in the small intestine during Giardia lamblia infection

Nitric oxide (NO) has been shown to inhibit Giardia lamblia in vitro and in vivo. This study sought to determine if Giardia infection induces arginase 1 (ARG1) expression in host macrophages to reduce NO production. Stimulations of RAW 264.7 macrophage-like cells with Giardia extract induced arginas...

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Vydáno v:Microbes Infect
Hlavní autoři: Maloney, Jenny, Keselman, Aleksander, Li, Erqiu, Singer, Steven M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461514/
https://ncbi.nlm.nih.gov/pubmed/25797399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2015.03.006
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