Simultaneous plasma and genital pharmacokinetics and pharmacodynamics of atazanavir and efavirenz in HIV-infected women starting therapy

Few studies characterize longitudinal female plasma and genital antiretroviral pharmacokinetics and pharmacodynamics. Among 20 regimen-naïve HIV-infected adult women initiating atazanavir- (n=9) or efavirenz-based therapy (n=11), we measured blood CD4+ T-lymphocytes, and paired plasma and genital HI...

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Udgivet i:J Clin Pharmacol
Main Authors: Neely, Michael, Louie, Stan, Xu, Jiaao, Anthony, Patricia, Thuvamontolrat, Kasalyn, Mordwinkin, Nicholas, Kovacs, Andrea
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461473/
https://ncbi.nlm.nih.gov/pubmed/25683232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.481
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