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Atazanavir–bilirubin interaction: a pharmacokinetic–pharmacodynamic model

PURPOSE: The aim of this work was to analyze the atazanavir–bilirubin relationship, using a new mathematical approach to pharmacokinetic–pharmacodynamic models, for competitive drug interactions based on Michaelis–Menten equations. PATIENTS AND METHODS: Because atazanavir induces an increase of plas...

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Detalhes bibliográficos
Main Authors: Lozano, Roberto, Domeque, Nieves, Apesteguia, Alberto-Fermin
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792011/
https://ncbi.nlm.nih.gov/pubmed/24106429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S48377
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