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Atazanavir–bilirubin interaction: a pharmacokinetic–pharmacodynamic model
PURPOSE: The aim of this work was to analyze the atazanavir–bilirubin relationship, using a new mathematical approach to pharmacokinetic–pharmacodynamic models, for competitive drug interactions based on Michaelis–Menten equations. PATIENTS AND METHODS: Because atazanavir induces an increase of plas...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Dove Medical Press
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3792011/ https://ncbi.nlm.nih.gov/pubmed/24106429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S48377 |
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