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Sequential Roles of Receptor Binding and Low pH in Forming Prehairpin and Hairpin Conformations of a Retroviral Envelope Glycoprotein

A general model has been proposed for the fusion mechanisms of class I viral fusion proteins. According to this model a metastable trimer, anchored in the viral membrane through its transmembrane domain, transits to a trimeric prehairpin intermediate, anchored at its opposite end in the target membr...

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Autori principali: Matsuyama, Shutoku, Delos, Sue Ellen, White, Judith M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC446138/
https://ncbi.nlm.nih.gov/pubmed/15254191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.15.8201-8209.2004
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