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Degenerate In Vitro Genetic Selection Reveals Mutations That Diminish Alfalfa Mosaic Virus RNA Replication without Affecting Coat Protein Binding

The alfalfa mosaic virus (AMV) RNAs are infectious only in the presence of the viral coat protein; however, the mechanisms describing coat protein's role during replication are disputed. We reasoned that mechanistic details might be revealed by identifying RNA mutations in the 3′-terminal coat...

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Autores principales: Rocheleau, Gail, Petrillo, Jessica, Guogas, Laura, Gehrke, Lee
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC446135/
https://ncbi.nlm.nih.gov/pubmed/15254175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.15.8036-8046.2004
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