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Degenerate In Vitro Genetic Selection Reveals Mutations That Diminish Alfalfa Mosaic Virus RNA Replication without Affecting Coat Protein Binding

The alfalfa mosaic virus (AMV) RNAs are infectious only in the presence of the viral coat protein; however, the mechanisms describing coat protein's role during replication are disputed. We reasoned that mechanistic details might be revealed by identifying RNA mutations in the 3′-terminal coat...

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Detalhes bibliográficos
Main Authors: Rocheleau, Gail, Petrillo, Jessica, Guogas, Laura, Gehrke, Lee
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC446135/
https://ncbi.nlm.nih.gov/pubmed/15254175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.15.8036-8046.2004
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