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High-resolution crystal structure of the leucine-rich repeat domain of the human tumour suppressor PP32A (ANP32A)

Acidic leucine-rich nuclear phosphoprotein 32A (PP32A) is a tumour suppressor whose expression is altered in many cancers. It is an apoptotic enhancer that stimulates apoptosome-mediated caspase activation and also forms part of a complex involved in caspase-independent apoptosis (the SET complex)....

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Publicat a:Acta Crystallogr F Struct Biol Commun
Autors principals: Zamora-Caballero, Sara, Šiaučiunaite-Gaubard, Lina, Bravo, Jeronimo
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461331/
https://ncbi.nlm.nih.gov/pubmed/26057796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X15006457
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