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Mammalian MutY homolog (MYH or MUTYH) protects cells from oxidative DNA damage
MutY DNA glycosylase homologs (MYH or MUTYH) reduce G:C to T:A mutations by removing misincorporated adenines or 2-hydroxyadenines paired with guanine or 7,8-dihydro-8-oxo-guanine (8-oxoG). Mutations in human the MYH (hMYH) gene are associated with the colorectal cancer predisposition syndrome MYH-a...
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| Publicado no: | DNA Repair (Amst) |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4461227/ https://ncbi.nlm.nih.gov/pubmed/24315136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2013.10.011 |
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