Structural and mutational analyses of dipeptidyl peptidase 11 from Porphyromonas gingivalis reveal the molecular basis for strict substrate specificity

The dipeptidyl peptidase 11 from Porphyromonas gingivalis (PgDPP11) belongs to the S46 family of serine peptidases and preferentially cleaves substrates with Asp/Glu at the P1 position. The molecular mechanism underlying the substrate specificity of PgDPP11, however, is unknown. Here, we report the...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sakamoto, Yasumitsu, Suzuki, Yoshiyuki, Iizuka, Ippei, Tateoka, Chika, Roppongi, Saori, Fujimoto, Mayu, Inaka, Koji, Tanaka, Hiroaki, Yamada, Mitsugu, Ohta, Kazunori, Gouda, Hiroaki, Nonaka, Takamasa, Ogasawara, Wataru, Tanaka, Nobutada
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4460893/
https://ncbi.nlm.nih.gov/pubmed/26057589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11151
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados