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Two-tiered coupling between flowing actin and immobilized N-cadherin/catenin complexes in neuronal growth cones

Neuronal growth cones move forward by dynamically connecting actin-based motility to substrate adhesion, but the mechanisms at the individual molecular level remain unclear. We cultured primary neurons on N-cadherin–coated micropatterned substrates, and imaged adhesion and cytoskeletal proteins at t...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Garcia, Mikael, Leduc, Cécile, Lagardère, Matthieu, Argento, Amélie, Sibarita, Jean-Baptiste, Thoumine, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4460488/
https://ncbi.nlm.nih.gov/pubmed/26038554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423455112
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