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Phosphorylation of the p34 subunit of human single-stranded-DNA-binding protein in cyclin A-activated G1 extracts is catalyzed by cdk-cyclin A complex and DNA-dependent protein kinase.

The human single-stranded-DNA-binding protein (HSSB, also called RP-A) is a trimeric complex (p70, p34, and p14) required for multiple functions in DNA transactions. We report here that the p34 subunit of HSSB was hyperphosphorylated by kinase activities present in G1 extract (obtained from HeLa cel...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Pan, Z Q, Amin, A A, Gibbs, E, Niu, H, Hurwitz, J
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1994
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44602/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8078885/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.18.8343
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