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BRAF Mutations in Canine Cancers

Activating mutations of the BRAF gene lead to constitutive activation of the MAPK pathway. Although many human cancers carry the mutated BRAF gene, this mutation has not yet been characterized in canine cancers. As human and canine cancers share molecular abnormalities, we hypothesized that BRAF gen...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Mochizuki, Hiroyuki, Kennedy, Katherine, Shapiro, Susan G., Breen, Matthew
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4460039/
https://ncbi.nlm.nih.gov/pubmed/26053201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129534
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