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THIS OLD HEART: CARDIAC AGING AND AUTOPHAGY

Autophagy, a cellular housekeeping process, is essential to maintain tissue homeostasis, particularly in long-lived cells such as cardiomyocytes. Autophagic activity declines with age and may explain many features of age-related cardiac dysfunction. In this review we summarize the current state of k...

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Bibliographische Detailangaben
Veröffentlicht in:J Mol Cell Cardiol
Hauptverfasser: Linton, Phyllis-Jean, Gurney, Michael, Sengstock, David, Mentzer, Robert M., Gottlieb, Roberta A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459942/
https://ncbi.nlm.nih.gov/pubmed/25543002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2014.12.017
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