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Impaired mitophagy at the heart of injury

Recent publications link mitophagy mediated by PINK1 and Parkin with cardioprotection and attenuation of inflammation and cell death. The field is in need of methods to monitor mitochondrial turnover in vivo to support the development of new therapies targeting mitochondrial turnover.

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Detalhes bibliográficos
Main Authors: Gottlieb, Roberta A., Mentzer, Jr., Robert M., Linton, Phyllis-Jean
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288037/
https://ncbi.nlm.nih.gov/pubmed/22082870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.12.18175
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