Defects in mitophagy promote redox-driven metabolic syndrome in the absence of TP53INP1

The metabolic syndrome covers metabolic abnormalities including obesity and type 2 diabetes (T2D). T2D is characterized by insulin resistance resulting from both environmental and genetic factors. A genome-wide association study (GWAS) published in 2010 identified TP53INP1 as a new T2D susceptibilit...

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Pubblicato in:EMBO Mol Med
Autori principali: Seillier, Marion, Pouyet, Laurent, N'Guessan, Prudence, Nollet, Marie, Capo, Florence, Guillaumond, Fabienne, Peyta, Laure, Dumas, Jean-François, Varrault, Annie, Bertrand, Gyslaine, Bonnafous, Stéphanie, Tran, Albert, Meur, Gargi, Marchetti, Piero, Ravier, Magalie A, Dalle, Stéphane, Gual, Philippe, Muller, Dany, Rutter, Guy A, Servais, Stéphane, Iovanna, Juan L, Carrier, Alice
Natura: Artigo
Lingua:Inglês
Pubblicazione: BlackWell Publishing Ltd 2015
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459819/
https://ncbi.nlm.nih.gov/pubmed/25828351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201404318
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