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Adenosine A2A receptors intrinsically regulate CD8+ T cells in the tumor microenvironment

Adenosine A2A receptor (A2AR) blockade enhances innate and adaptive immune responses. However, mouse genetic studies have shown that A2AR deletion does not inhibit the growth of all tumor types. In the current study, we showed that growth rates for ectopic melanoma and bladder tumors are increased i...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Cekic, Caglar, Linden, Joel
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459794/
https://ncbi.nlm.nih.gov/pubmed/25341542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3581
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