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Adenosine A2A receptors intrinsically regulate CD8+ T cells in the tumor microenvironment

Adenosine A2A receptor (A2AR) blockade enhances innate and adaptive immune responses. However, mouse genetic studies have shown that A2AR deletion does not inhibit the growth of all tumor types. In the current study, we showed that growth rates for ectopic melanoma and bladder tumors are increased i...

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Bibliografische gegevens
Gepubliceerd in:Cancer Res
Hoofdauteurs: Cekic, Caglar, Linden, Joel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459794/
https://ncbi.nlm.nih.gov/pubmed/25341542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3581
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