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Extracellular adenosine regulates naive T cell development and peripheral maintenance
Adenosine produced as a byproduct of metabolic activity is present in all tissues and produces dose-dependent suppression of TCR signaling. Naive T cell maintenance depends on inhibition of TCR signals by environmental sensors, which are yet to be fully defined. We produced mice with a floxed adenos...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3832923/ https://ncbi.nlm.nih.gov/pubmed/24145516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20130249 |
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