Association of HSD11B1 polymorphic variants and adipose tissue gene expression with metabolic syndrome, obesity and type 2 diabetes mellitus: a systematic review

The HSD11B1 gene is highly expressed in abdominal adipose tissue, and the enzyme it encodes catalyzes the interconversion of inactive cortisone to hormonally active cortisol. Genetic abnormalities of HSD11B1 have been associated with the development of abnormal glucose metabolism and body fat distri...

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Dettagli Bibliografici
Pubblicato in:Diabetol Metab Syndr
Autori principali: do Nascimento, Filipe Valvassori, Piccoli, Vanessa, Beer, Mayara Abichequer, von Frankenberg, Anize Delfino, Crispim, Daisy, Gerchman, Fernando
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459686/
https://ncbi.nlm.nih.gov/pubmed/26056536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13098-015-0036-1
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