Association of HSD11B1 polymorphic variants and adipose tissue gene expression with metabolic syndrome, obesity and type 2 diabetes mellitus: a systematic review

The HSD11B1 gene is highly expressed in abdominal adipose tissue, and the enzyme it encodes catalyzes the interconversion of inactive cortisone to hormonally active cortisol. Genetic abnormalities of HSD11B1 have been associated with the development of abnormal glucose metabolism and body fat distri...

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Detalhes bibliográficos
Publicado no:Diabetol Metab Syndr
Main Authors: do Nascimento, Filipe Valvassori, Piccoli, Vanessa, Beer, Mayara Abichequer, von Frankenberg, Anize Delfino, Crispim, Daisy, Gerchman, Fernando
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459686/
https://ncbi.nlm.nih.gov/pubmed/26056536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13098-015-0036-1
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