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Biomimetic three-dimensional tissue models for advanced high-throughput drug screening

Most current drug screening assays used to identify new drug candidates are 2D cell-based systems, even though such in vitro assays do not adequately recreate the in vivo complexity of 3D tissues. Inadequate representation of the human tissue environment during a preclinical test can result in inacc...

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Détails bibliographiques
Publié dans:J Lab Autom
Auteurs principaux: Nam, Ki-Hwan, Smith, Alec S.T., Lone, Saifullah, Kwon, Sunghoon, Kim, Deok-Ho
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459652/
https://ncbi.nlm.nih.gov/pubmed/25385716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2211068214557813
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